關於「AIM2 inflammasome」標籤，搜尋引擎有相關的訊息討論：

AIM2 inflammasome activation and regulation: A structural perspective。

2017年8月13日 · FP assays demonstrated that both AIM2PYD and AIM2FL+dsDNA accelerated spontaneous filament formation of ASCPYD (Lu et al., 2014b). EM ...： tw | tw。

The AIM2 inflammasome is essential for host-defense against ...。

Recently, AIM2 was shown to bind DNA and engage ASC to form a caspase-1 activating inflammasome. Using Aim2-deficient mice, we reveal a central role for ...： tw | tw。

AIM2 inflammasome surveillance of DNA damage shapes ... - Nature。

2020年4月8日 · The sensing of DNA damage by the AIM2 inflammasome promotes the death ... astrocytes and oligodendrocyte lineage cells) in Casp1fl/flNescre ...。

Distinct axial and lateral interactions within homologous filaments ...。

2021年5月12日 · AIM2-ASC inflammasomes are filamentous signalling platforms that play ... the filament cryo-EM structure of the inflammasome receptor AIM2, ...。

The AIM2 inflammasome: Sensor of pathogens and cellular ...。

2017年12月16日 · AIM2 activation initiates the assembly of the inflammasome, an innate immune complex that leads to the activation of inflammatory caspases. This ...。

The DNA-sensing AIM2 inflammasome controls radiation-induced ...。

2016年11月11日 · (A) WT mice were cohoused with Casp1fl/fl;VillinCre+ mice for at least 2 weeks and then exposed to 14.2 Gy of SBI. Kaplan-Meier survival ...。

The DNA-sensing AIM2 inflammasome controls radiation ... - Science。

Jr. and Voelz G. L., Major radiation exposure—what to expect and how to respond. N. Engl. J. Med. 346, 1554–1561 ( ...。

Inhibition of AIM2 inflammasome activation by a novel transcript ...。

Mouse p202 is a disease locus for lupus and a dominant-negative inhibitor of AIM2 inflammasome activation. A human homolog of p202 has not been identified ...。

Antagonism of the STING Pathway via Activation of the AIM2 ...。

2016年4月1日 · Whether the AIM2 inflammasome influences STING pathway activation has not ... gels and transferred onto Immobilon-FL membranes (Millipore).。

Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain ...。

is a major cytosolic dsDNA sensor that forms an inflammasome with the adapter ASC and procaspase-1 to activate proinflammatory cytokine processing (. 1.